[Anti-androgen therapy in the female]

Besides the various androgenic activities actions in women, signs of androgenisation such as acne, seborrhoe, hirsutism and alopecia, play an important clinical role and require a proper diagnostic evaluation and individualised medical treatment. After development and thorough clinical evaluation of antiandrogen, a variety of therapeutic possibilities have become available. The main antiandrogens are: Cyproterone acetate, chlormadinone acetate and spironolactone. They are used in mono- or combination-therapy regimens. Means of application (oral, parenteral), dosages used and different forms of combination therapies are presented under practical aspects. The effects of such treatment modalities are outlined.