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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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Asymmetric syntheses of (-)-mitorubrin and related azaphilone natural products
1Department of Chemistry and Center for Chemical Methodology and Library Development, Boston University, Boston, MA 02215, USA
Organic Letters
|October 20, 2006
Abstract:
Asymmetric syntheses of (-)-mitorubrin and related azaphilone natural products are reported. Key steps involve copper-mediated, enantioselective oxidative dearomatization to prepare the azaphilone core and olefin cross-metathesis for side-chain installation. [reaction: see text]
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