Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Quantification of prostate movements during radiotherapy].

X Artignan1, M Rastkhah, J Balosso

  • 1Service de Radiothérapie, CHU de Grenoble, Boulevard de la Chantourne, 38700 La Tronche, France. xartignan@chu-grenoble.fr

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|October 20, 2006
PubMed
Summary

Understanding prostate motion is crucial for reducing radiation oncology uncertainties. Rectal filling significantly impacts prostate movement, necessitating adaptive strategies for precise treatment delivery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2024
Same author

Indication and perspectives of radiation therapy in the setting of de-novo metastatic prostate cancer.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2023
Same author

Thoughts about the evolution of cancer registries in France.

European annals of otorhinolaryngology, head and neck diseases·2023
Same author

Radiotherapy of skin adnexal carcinoma.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2023
Same author

Radiotherapy of lymphomas.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2021
Same author

RadioTransNet: Preclinical research network coordinated at the SFRO and SFPM.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2021

Area of Science:

  • Radiation Oncology
  • Medical Imaging
  • Biophysics

Background:

  • Minimizing treatment uncertainties is a key challenge in radiation oncology.
  • Accurate prostate localization is essential for defining treatment margins and avoiding mispositioning.

Purpose of the Study:

  • To analyze prostate motion patterns during radiation therapy.
  • To identify factors influencing prostate movement.
  • To inform strategies for improving treatment accuracy.

Main Methods:

  • Review of techniques for quantifying prostate motion (CT-scan, cone-beam CT, ultrasound, markers).
  • Analysis of prostate movement amplitudes in different directions (anterior-posterior, cranial-caudal, lateral).
  • Investigation of factors causing motion, primarily rectal and bladder filling status.

Related Experiment Videos

Main Results:

  • Long-term prostate movements show standard deviations of 3 mm (anterior-posterior), 1-2 mm (cranial-caudal), and 0.5-1 mm (lateral).
  • Rectal filling state is the primary cause of both long-term and intra-session prostate movements.
  • Intra-session movements, particularly with an empty rectum, are expected to be less than 3 mm.

Conclusions:

  • Rectal filling status is the principal driver of prostate motion, impacting treatment accuracy.
  • Understanding these motion patterns allows for better margin definition in radiation oncology.
  • Real-time imaging and adaptive dosimetry are ideal for precise prostate localization within treatment timeframes.