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Esophageal actinomycosis.

Fu-Tsan Chou1, Ken-Sheng Cheng, I-Ping Chiang

  • 1Department of Internal Medicine/Pathology, Division of Hepatology and Gastroenterology, China Medical University Hospital, Taichung, Taiwan.

Advances in Therapy
|October 20, 2006
PubMed
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Esophageal actinomycosis, a rare fungal infection, can cause painful swallowing and difficulty eating. Prompt diagnosis via endoscopy and biopsy, followed by antibiotics, leads to effective treatment and healing.

Area of Science:

  • Gastroenterology
  • Infectious Diseases

Background:

  • Esophageal actinomycosis is a rare condition affecting both immunocompetent and immunocompromised individuals.
  • Heavy alcohol use is a potential risk factor, as illustrated by a case study.

Observation:

  • A 41-year-old male presented with a two-week history of worsening odynophagia and dysphagia.
  • Upper gastrointestinal endoscopy revealed esophageal ulceration.
  • Esophageal biopsy confirmed co-infection with Actinomyces and Candida.

Findings:

  • Treatment with intravenous penicillin G followed by oral amoxicillin resulted in clinical improvement.
  • Repeat endoscopy demonstrated healing of esophageal ulceration and resolution of Actinomyces infection.

Implications:

Related Experiment Videos

  • Esophageal actinomycosis should be considered in the differential diagnosis for odynophagia and dysphagia.
  • Thorough evaluation with upper gastrointestinal endoscopy and pathological examination is crucial for accurate diagnosis and management.