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Updated: Jul 19, 2026
12:04
The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Systemic lupus erythematosus.
N D Jayakumar1, R Jaiganesh, O Padmalatha
1Department of Periodontitis, SIMATS, Chennai.
Summary
Desquamative gingival lesions, often linked to skin conditions, can manifest in Systemic Lupus Erythematosus (SLE). This case highlights oral involvement in a 36-year-old female patient with SLE.
Area of Science:
- Oral Medicine
- Dermatology
- Immunology
Background:
- Desquamative gingival lesions are inflammatory conditions not caused by plaque.
- These lesions are clinical indicators of underlying dermatological diseases.
- Systemic Lupus Erythematosus (SLE) is a rare dermatosis that can present with oral manifestations.
Observation:
- A case report details a 36-year-old female patient with Systemic Lupus Erythematosus.
- The patient presented with desquamative oral lesions specifically affecting the gingiva.
- Clinical presentation, histological examination, and diagnostic findings were documented.
Findings:
- The gingival lesions were consistent with oral manifestations of Systemic Lupus Erythematosus.
- Histological and investigatory findings supported the diagnosis of SLE.
- The case underscores the link between dermatological conditions and oral health.
Implications:
- Recognizing desquamative gingival lesions as potential indicators of systemic diseases like SLE is crucial.
- Early diagnosis and management of oral manifestations can improve patient outcomes.
- This case contributes to understanding the diverse clinical presentations of Systemic Lupus Erythematosus.
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