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siRNA efficiency: structure or sequence-that is the question

Jens Kurreck1

  • 1Institute for Chemistry and Biochemistry, Free University Berlin, Berlin, Germany.

Journal of Biomedicine & Biotechnology
|October 24, 2006
PubMed
Summary

Identifying effective small interfering RNAs (siRNAs) for RNA interference (RNAi) is crucial. This review explores factors beyond thermodynamics, like target accessibility, to improve gene silencing success.

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