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Mild left ventricular dysfunction is associated with thrombogenicity in cardioembolic stroke

Hyung-Min Kwon1, Jong-Ho Park, Jeong-Min Kim

  • 1Department of Neurology, Kyunghee University East-West Neo Medical Center, Seoul, Korea.

European Neurology
|October 24, 2006
PubMed

Insights

Transesophageal echocardiography (TEE) can identify cardiac thrombus in stroke patients. Perform TEE in patients with atrial fibrillation or reduced left ventricular ejection fraction after suspected cardioembolic stroke.

Area of Science:

  • Cardiology
  • Neurology
  • Medical Imaging

Background:

  • Transesophageal echocardiography (TEE) is crucial for detecting left cardiac thrombus (LCT) and spontaneous echocardiographic contrast (SEC).
  • Identifying patients who would benefit most from TEE for suspected cardioembolic stroke is essential.

Purpose of the Study:

  • To determine risk groups for performing TEE in patients with suspected cardioembolic stroke.
  • To correlate TEE findings of thrombogenicity with patient characteristics.

Main Methods:

  • Analyzed 146 patients with suspected cardioembolic stroke.
  • Utilized TEE to assess for LCT and SEC, indicating thrombogenicity.
  • Evaluated associations between thrombogenicity and demographic, clinical, and echocardiographic factors.

Main Results:

  • Thrombogenicity was observed in 27.3% of patients (40/146), with 10 LCT and 30 SEC.
  • Independent predictors of thrombogenicity included atrial fibrillation (OR 7.14) and left ventricular ejection fraction ≤50% (OR 4.01).

Conclusions:

  • TEE is recommended for patients with suspected cardioembolic stroke and mildly reduced left ventricular dysfunction (ejection fraction ≤50%).
  • Atrial fibrillation is a significant risk factor for thrombogenicity detected by TEE.
Abstract

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