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Updated: Jul 19, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Changes in performance over time on the Bayley Scales of Infant Development II when administered to infants at high
1Grandview Children's Centre, Oshawa, Ontario, Canada. Karen.Koseck@grtc.ca
Insights
Infants exposed to prenatal drugs showed declining cognitive and motor skills over time. Perinatal medical concerns impacted motor skills differently, highlighting the need for distinct developmental assessments.
Area of Science:
- Developmental Psychology
- Pediatric Neurology
- Neonatal Care
Background:
- Infants at high risk for developmental disabilities require careful monitoring.
- Prenatal drug exposure and perinatal medical concerns are significant risk factors.
- Understanding developmental trajectories is crucial for early intervention.
Purpose of the Study:
- To analyze longitudinal changes in cognitive and motor performance.
- To assess performance on the Bayley Scales of Infant Development II (BSID-II).
- To compare developmental trajectories in infants with prenatal drug exposure versus perinatal medical concerns.
Main Methods:
- Study included 53 high-risk infants: 34 with prenatal drug exposure (DE group) and 19 with perinatal medical concerns (PMC group).
- Cognitive and motor performance measured using BSID-II at two time points: under one year (mean 6.99 months) and 17-22 months (mean 18.24 months).
- Analysis focused on changes in Mental and Motor Scale scores over time for both groups.
Main Results:
- Both groups exhibited a significant decrease in cognitive performance over time (p < 0.05).
- Motor performance showed divergent changes: an increase in the PMC group and a decrease in the DE group (p < 0.01).
- These findings indicate distinct developmental patterns based on risk factors.
Conclusions:
- Developmental trajectories differ significantly between infants with prenatal drug exposure and those with perinatal medical concerns.
- Separate analysis and tailored interventions are recommended for these distinct high-risk infant populations.
- Longer-term follow-up with repeated assessments is necessary to fully understand developmental outcomes.
Purpose:
The purpose of this study was to analyze changes in performance over time on the Bayley Scales of Infant Development II (BSID-II) in a sample of infants at high risk of developmental disabilities.
Methods:
Cognitive and motor performance of 53 infants, 34 with prenatal drug exposure (DE group) and 19 with perinatal medical concerns (PMC group), was measured at under one year of age (mean = 6.99 months) and again at 17-22 months of age (mean = 18.24 months). Changes in performance on both the Mental and Motor Scales over time were analyzed.
Results:
Over time, cognitive performance decreased for both groups (p < 0.05). Rate of change in motor performance increased for the PMC group and decreased for the DE group (p < 0.01).
Conclusions:
Developmental changes over time should be studied separately for infants prenatally exposed to drugs and infants with perinatal medical concerns. Longer term follow-up with several repeat assessments would be desirable.
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