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Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

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Nephrotic Syndrome I : Introduction

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Methods of Documentation I: Source-Oriented Records01:18

Methods of Documentation I: Source-Oriented Records

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Key Attributes include the following:
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

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SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

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Updated: Jul 19, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
05:06

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review

Published on: March 27, 2026

[SAPHO syndrome--clinical report].

Michele De Santis1, Jorge Fortuna

  • 1Serviço de Medicina, Centro Hospitalar de Coimbra. iperpicchio76@hotmail.com

Acta Reumatologica Portuguesa
|October 25, 2006
PubMed
Summary

SAPHO Syndrome, a rare skin and bone disease, presents with varied symptoms and uncertain treatment responses. This review covers a case study and literature, highlighting key aspects of this condition.

Area of Science:

  • Rheumatology
  • Dermatology
  • Orthopedics

Background:

  • SAPHO Syndrome (Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis) is a rare autoinflammatory disorder affecting skin and bone.
  • First described in the 1980s, it impacts the anterior chest wall and costal areas, presenting as a 'Skin-Bone Disease'.
  • The condition affects all age groups and sexes equally, with variable clinical manifestations.

Observation:

  • Clinical symptoms of SAPHO Syndrome can differ significantly based on the age of onset.
  • The response to treatment for SAPHO Syndrome is often unpredictable.
  • The true prevalence of SAPHO Syndrome remains unknown, contributing to its classification as a rare disease.

Findings:

  • This article presents a clinical case of SAPHO Syndrome.

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Last Updated: Jul 19, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
05:06

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review

Published on: March 27, 2026

  • A comprehensive literature review on SAPHO Syndrome is provided.
  • Key aspects of SAPHO Syndrome, including diagnosis and management, are discussed.
  • Implications:

    • Understanding SAPHO Syndrome is crucial for accurate diagnosis and effective patient management.
    • Further research into the prevalence and treatment of SAPHO Syndrome is warranted.
    • This review contributes to the existing knowledge base for clinicians managing patients with SAPHO Syndrome.