[Radiologic findings in Gorham-Stout syndrome]
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Updated: Jul 19, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Bernardo Cano1, Sonia Insa, Carlos Cifrián
1Servicio de Radiodiagnóstico de adultos, Hospital La Fe, Valencia, España. cano_bernar@gva.es
Abstract:
Gorham-Stout syndrome, also called "disappearing bone disease" or idiopathic massive osteolysis, is a rare disease of unknown etiology and pathogenesis. It is characterized by rapidly progressive localized massive osteolysis associated to a proliferation of vascular structures of benign origin in which the absence of new bone formation is representative. We present two cases (a six-year-old boy with affected right ulna, and a 15-year-old girl with right rib affection associated to chylothorax) of this disease with the characteristic clinical, histological, and imaging findings.
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