Related Experiment Video
Updated: Jul 19, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
Published on: September 4, 2017
An inter-hospital comparison of patient dose based on clinical indications
W Teeuwisse1, J Geleijns, W Veldkamp
1Department of Radiology, Leiden University Medical Center, The Netherlands. w.m.teeuwisse@lumc.nl
Abstract:
Patient dose is usually estimated for a single radiographic projection or computed tomography (CT) series. In this study, patient dose was calculated for predefined clinical indications (24 radiography, 11 CT). Members of the radiology staff of each of 11 hospitals were trained in dose measurement and calculation techniques. Based on clinical indications participants decided on imaging protocols and calculated cumulative effective dose for a complete examination. Effective dose ranged from <1 microSv to 0.6 mSv for examinations with radiographs and from 0.2 to 12 mSv for CT scans. Differences in the imaging protocols contributedd to a substantial variation in patient dose. For mammography, average glandular dose (AGD) was estimated for 32-, 53- and 90-mm compressed breast thicknesses, with a median value of 0.74, 1.74 and 3.40 mGy, respectively. The results presented here demonstrate that a pragmatic choice of dosimetry methods enables local staff to estimate effective dose. The inclusion of imaging protocols in the dose surveys provided a broader view on the variations in patient dose between hospitals.
Related Concept Videos
Dosage Regimen: Individualization
Bioequivalence of Drugs: Drugs with Multiple Indications
Drug Dosing: Infants and Children
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant
Hazard Ratio
For example, in a clinical trial evaluating a...

