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Radial artery diameter and vasodilatory properties after transradial coronary angiography

Erik Madssen1, Petter Haere, Rune Wiseth

  • 1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.

The Annals of Thoracic Surgery
|October 26, 2006
PubMed

Insights

Transradial coronary angiography reduces radial artery diameter long-term, but preserves its vasodilatory function. This structural change means the catheter-exposed radial artery may not be ideal for coronary bypass grafting.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Ultrasound

Background:

  • The radial artery is a potential conduit for coronary revascularization.
  • Transradial approach is increasingly preferred for percutaneous coronary procedures.
  • This approach may impact the radial artery's suitability as a bypass graft due to induced trauma.

Purpose of the Study:

  • To assess the long-term effects of transradial coronary angiography on radial artery diameter.
  • To evaluate the impact on radial artery vasodilatory properties using ultrasound.

Main Methods:

  • High-resolution ultrasound was used to examine 30 patients 10-14 months post-transradial angiography.
  • The exposed right radial artery was compared to the unexposed left radial artery.
  • Flow-mediated (FMD) and nitroglycerin-mediated vasodilation (NMD) were assessed.

Main Results:

  • The right radial artery diameter was significantly reduced compared to the left (p < 0.01).
  • Both FMD and NMD were preserved in the exposed radial artery (not significant).
  • Despite preserved vasodilation, the reduced baseline diameter resulted in a smaller lumen post-stimuli.

Conclusions:

  • Radial artery diameter diminishes one year after transradial angiography, while vasodilatory properties remain intact.
  • Preserved vasodilatory capacity is favorable for bypass graft suitability.
  • Long-term structural changes suggest caution in using catheter-exposed radial arteries for coronary artery revascularization.
Abstract

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