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Updated: Jul 19, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
[Morphological characteristics of craniofacial complex in adults with skeletal class III malocclusions]
1The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. junlin2@126.com
Objective:
To identify the morphological characteristics of craniofacial structure in patients with skeletal class III malocclusions.
Methods:
The study samples consisted of 63 lateral cephalometric radiographs of adult with class I malocclusion (32 male and 31 female, ages >17 years) and 27 patients with skeletal class III malocclusion (14 male and 13 female, ages >17 years, ANB >-3). The proportion of posterior cranial base and the mandibular length were measured.
Result:
There was an increase in total mandibular length (Go-Gn, Cd-Gn) in female patients with class III malocclusion. There was a decrease in the posterior cranial base length (S-Ar) and an increase in mandibular length (Go-Gn) in male patients with class III malocclusion.
Conclusion:
The major craniofacial characteristics of skeletal class III malocclusion compared with those of class I malocclusion are smaller posterior cranial base in males and larger mandibular length in both sexes.
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