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Candida albicans pacemaker site infection.

T J Cohen1, V G Pons, J Schwartz

  • 1Department of Medicine, University of California, San Francisco, California.

Pacing and Clinical Electrophysiology : PACE
|February 1, 1991
PubMed
Summary
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A diabetic patient developed a rare Candida albicans pacemaker infection despite sterile procedures. The infection required device removal and treatment, highlighting infection risks in diabetic patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Device Infections

Background:

  • Pacemaker implantation is a common procedure for managing heart block.
  • Diabetes mellitus is a known risk factor for various infections.
  • Candida albicans is an opportunistic fungal pathogen.

Observation:

  • A 69-year-old male diabetic with lymphocytopenia underwent pacemaker implantation for complete heart block.
  • Despite prophylactic measures, a fungal infection (Candida albicans) of the pacemaker site occurred.
  • The infection necessitated pacemaker explantation and systemic antifungal therapy.

Findings:

  • Successful treatment involved pacemaker explantation and amphotericin B therapy.
  • A new pulse generator was implanted on the contralateral side.

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  • The patient remained free of infection at a 2-year follow-up.

    • Implications:

    • This case highlights the increased susceptibility of diabetic patients to fungal infections, specifically Candida albicans.
    • It underscores the importance of vigilance for device-site infections in immunocompromised patients.
    • Management strategies for pacemaker infections in diabetic individuals may need careful consideration.