Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

Photoreceptors and Plant Responses to Light

Photoreceptors and Plant Responses to Light

Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.

Anatomy of the Eyeball

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An Alternative Mechanism for the Anti-Myopia Effectiveness of Diffusion Optics Technology (DOT) Lenses.

Translational vision science & technology·2025

Same author

Comment on: "Polymer Co-Coating of Gold Nanoparticles Enables Their Integration Into Contact Lenses for Stable, Selective Ocular Light Filters".

Advanced materials interfaces·2023

Same author

Limited bandwidth short-wavelength light produces slowly-developing myopia in tree shrews similar to human juvenile-onset myopia.

Vision research·2022

Same author

Chromatically simulated myopic blur counteracts a myopiagenic environment.

Experimental eye research·2022

Same author

DeBruyn and Casagrande manuscripts on tree shrew retinal ganglion cells as a basis for cross-species retina research.

Visual neuroscience·2022

Same author

Amber light treatment produces hyperopia in tree shrews.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2021

Search research articles

Related Experiment Videos

Darkness causes myopia in visually experienced tree shrews.

Thomas T Norton¹, Angela O Amedo, John T Siegwart

¹Department of Vision Sciences, University of Alabama at Birmingham, 924 S. 18th Street, Birmingham, AL 35294, USA. trnorton@icare.opt.uab.edu

Investigative Ophthalmology & Visual Science

|October 27, 2006

Summary

This summary is machine-generated.

Continuous darkness promotes myopia in juvenile tree shrews, indicating that visual guidance is crucial for maintaining normal vision and emmetropia. Absence of light can induce myopia, even in eyes previously corrected for refractive errors.

Related Experiment Videos

Area of Science:

Ophthalmology
Animal Models of Visual Development
Myopia Research

Background:

Emmetropization is the process by which the eye achieves normal visual acuity.
Light exposure plays a critical role in regulating eye growth and refractive development.
Understanding factors influencing refractive error is key to addressing myopia prevalence.

Purpose of the Study:

To investigate the impact of continuous darkness on refractive state and vitreous chamber depth in juvenile tree shrews.
To determine if myopia induced by minus-lens wear in tree shrew eyes can recover in darkness.
To assess the role of light in maintaining emmetropia and preventing myopia.

Main Methods:

Juvenile tree shrews were exposed to continuous darkness for 10 days after initial refractive measurements.
Ocular components and refractive state were measured before and after the dark period.
A control group received standard lighting, and a separate group experienced darkness after induced myopia.

Main Results:

Dark-reared tree shrew eyes shifted towards myopia (-4.3 D) with increased vitreous chamber depth.
Eyes that developed myopia from minus-lens wear worsened in darkness, and control eyes also became myopic.
Normal-lighting controls achieved stable hyperopia (0.7 D).

Conclusions:

Maintaining emmetropia is an active process requiring continuous visual input.
Absence of light is myopiagenic in tree shrews adapted to normal diurnal lighting.
Continued visual guidance is necessary for refractive stability and recovery from induced myopia.