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Updated: Jul 19, 2026

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect
Published on: April 14, 2026
[Spontaneous and post-therapeutic cartilage repair: evaluation criteria]
P Mainil-Varlet1, R Fischer, H Jülke
1Institut für Pathologie, Universität, Bern. pierre.mainil@pathology.unibe.ch
Abstract:
Articular cartilage has poor reparative capacities, and once damaged cartilage lesions remain chronic and can lead to osteoarthritis. Over the last decade, several innovative therapies have been introduced to promote the regeneration of articular cartilage while sustaining sufficient mechanical stress and permitting a pain free motion. An important measure of outcome is the morphological characterization of the repair tissue in order to allow for cross-study evaluation. The International Cartilage Repair Society has developed a analogue visual scale to quantify repair tissue, which is described in this paper.
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