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[Urolithiasis in children in Tunisia: current features based on a series of 104 cases]
Akram Alaya1, Mohsen Belgith, Riadh Jouini
1Laboratoire de Biochimie-Toxicologie, CHU Monastir, Tunisie. akram_alaya@yahoo.co.uk
Insights
Pediatric urolithiasis in Tunisia shows a male predominance and is often linked to urinary tract infections. Whewellite is the most common stone type, but age influences stone composition, requiring tailored diagnostic approaches.
Area of Science:
- Pediatric Nephrology
- Urology
- Mineralogy
Context:
- Urolithiasis in children presents unique challenges compared to adults.
- Understanding evolving trends in pediatric urolithiasis is crucial for effective management.
- Tunisia has seen continuous changes in the clinical and laboratory characteristics of childhood urolithiasis since the 1980s.
Purpose:
- To define the current status of urolithiasis in Tunisian children.
- To analyze the clinical and laboratory features of pediatric urolithiasis in Tunisia.
- To identify trends in stone composition and affected urinary tract regions.
Summary:
- This retrospective study analyzed 104 Tunisian children hospitalized for urolithiasis.
- Findings indicate a male predominance (sex ratio 1.53), with urinary tract infections being the most common clinical feature (28.8%).
- Upper tract stones occurred in 75% of cases. Whewellite was the predominant crystalline species (80% in children, 57.1% in infants), with ammonium acid urate more frequent in infants.
Impact:
- Highlights the changing epidemiological landscape of pediatric urolithiasis in Tunisia.
- Emphasizes the importance of age as a factor in the etiological work-up of pediatric urolithiasis.
- Provides data to inform clinical practice and public health strategies for childhood kidney stones in the region.
Unlabelled:
The clinical and laboratory characteristics of urolithiasis in Tunisian children have evolved continuously since the 1980s. This retrospective study defines the current status of urolithiasis in children in Tunisia.
Patients And Methods:
All 104 children (age: 8-192 months) of our series were hospitalized for urolithiasis. A first-line metabolic, urine and plasma work-up was performed in 96 patients. Physical and chemical analysis of the stones was performed by stereomicroscopy and infrared spectroscopy, respectively. Statistical analysis of the results was performed with SPSS 11.0 software. The Chi-square test was used for comparison of percentages.
Results:
Our study shows a male predominance of urolithiasis with a sex ratio of 1.53. The clinical features were dominated by urinary tract infections (28.8%). Stones were situated in the upper tract in 75% of cases and the lower tract in 25% of cases. Urine culture was positive in 15 patients. Identification of the crystalline composition showed that whewellite was the most frequent crystalline species in children (80.0%) and infants (57.1%). Ammonium acid urate was more frequent in infants.
Conclusion:
In this study, we observed changes in the epidemiological characteristics (bladder stones and infection stones) of urolithiasis in children over the last decade in Tunisia. The patient's age is an important factor that must be taken into account during aetiopathogenic work-up.
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