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Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
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Study of the interaction between S(--) bupivacaine and 2-hydroxypropyl-beta-cyclodextrin

Carolina Morales Moraes1, Priscila Abrami, Eneida de Paula

  • 1Faculty of Pharmacy, University of Sorocaba, Cidade Universitária, Rodovia Raposo Tavares, Km 92,5, 18023-000 Sorocaba, SP, Brazil.

International Journal of Pharmaceutics
|October 31, 2006
PubMed
Summary

This study characterizes a stable inclusion complex between the local anesthetic S(--) bupivacaine and 2-hydroxypropyl-beta-cyclodextrin. The complexation enhances drug solubility and provides thermodynamic data for potential pain treatment formulations.

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