Related Experiment Video
Updated: Jul 19, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Cartilaginous septum deviation in children with cleft lip, alveolus and palate--an MRI analysis
Thomas Bayerlein1, Peter Proff, Thomas Koppe
1Department of Orthodontics, Preventive and Pediatric Dentistry, Ernst Moritz Arndt University, Greifswald, Germany. kieferorthopaedie@uni-greifswald.de
Insights
Nasal septum deviation in infants with cleft lip and palate is linked to cleft size. Deviation occurs only in unilateral cases, worsening as the cleft grows, impacting facial development.
Area of Science:
- Craniofacial Surgery
- Pediatric Radiology
- Medical Imaging
Background:
- Cleft lip, alveolus, and palate (CLAP) are common congenital conditions.
- Nasal septum deviation is a frequent complication in CLAP patients.
- Understanding the relationship between cleft size and septal deviation is crucial for surgical planning.
Purpose of the Study:
- To assess the correlation between cleft size and the degree of cartilaginous nasal septum deviation in infants with CLAP.
- To determine if septal deviation differs between unilateral and bilateral clefts.
Main Methods:
- MRI examinations were performed on six neonates (5-20 days old) with CLAP using a 1.0 Tesla scanner.
- Maximal cleft size (mm) and nasal septum deviation angle (degrees) were quantified.
- Correlation analysis was performed between cleft size and septal deviation.
Main Results:
- No nasal septum deviation was observed in two infants with bilateral clefts.
- Three infants with unilateral left-sided clefts showed rightward deviation.
- One infant with a unilateral right-sided cleft exhibited leftward deviation; deviation increased with cleft size in all unilateral cases.
Conclusions:
- Cartilaginous nasal septum deviation is present in unilateral CLAP cases.
- The degree of deviation is more pronounced with larger cleft sizes.
- Findings suggest a direct relationship between unilateral cleft severity and septal malalignment.
Introduction:
This study aimed to investigate by MRI examination the degree of deviation of the cartilaginous septum in relation to cleft size in patients with cleft lip, alveolus and palate.
Material And Methods:
Six children with cleft lip, alveolus and palate at age 5-20 days were examined with a 1.0 Tesla scanner using a head coil. The following parameters were evaluated: maximal cleft size (millimeter) and degree of the nasal septum deviation from the median-sagittal plane (degrees).
Results:
Two children with bilateral clefts had no deviation; 3 children with unilateral (left-sided) cleft had a deviation to the right and 1 patient with a unilateral right-sided cleft a deviation to the left side. In all 4 patients, the degree of the nasal septum deviation increased with cleft size.
Conclusion:
Cartilaginous nasal septum deviation was noticed only in patients with unilateral cleft lip and palate toward the non-cleft side and was greater with increasing cleft sizes.
More Related Videos
Related Concept Videos
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Alveoli and Alveolar Ducts

