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Updated: Jul 19, 2026
Modeling Cataract Surgery in Mice
Published on: December 1, 2023
The impact of cataract surgery on visual functioning, vision-related disability and psychological distress: a
Janine G Walker1, Kaarin J Anstey, Michael P Hennessy
1Centre for Mental Health Research, Australian National University, Canberra, Australia. janine.walker@anu.edu.au
Purpose:
Determine whether there are changes in visual functioning, vision-related disability, health status and mood after cataract surgery.
Methods:
45 adults (mean age = 73.7 years) with bilateral cataract needing surgery for the first eye were recruited from public ophthalmology clinics. The Visual Functioning-14 survey assessed visual disability. Minimal angle of resolution tested visual acuity, and the Melbourne Edge Test examined contrast sensitivity. Demographic, psychological, health and medication use variables were examined. Participants were randomized to either an intervention or control arm. Controls were assessed on two occasions at a 3-month interval before having surgery. The intervention group was assessed 1-2 weeks before surgery and then reassessed 3 months after surgery.
Results:
Visual functioning improved for those who had cataract surgery with better visual acuity in the better (P = 0.010) and worse (P = 0.028) eye compared with controls. The intervention group reported fewer difficulties with overall vision-related disability (P = 0.0001), reading (P = 0.004) and instrumental activities of daily living (P = 0.010) post-surgery compared with controls. People with improved depression scores (P = 0.048) after surgery had less difficulty with reading compared with those with unchanged or worsened depression scores. Cataract surgery did not improve health status.
Conclusions:
First eye cataract surgery is effective in improving outcomes in visual functioning and disability. Improved mood after surgery was related to less vision-related disability compared with unchanged or worse depression.
