Related Experiment Video
Updated: Jul 19, 2026

04:34
Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Eosinophilic cellulitis presented with semicircular pattern
Ozlem Karabudak1, Bilal Dogan, Oktey Taskapan
1Haydarpasa Training Hospital, Department of Dermatology, Camlica Campus, Istanbul, Turkey. okarabudak@yahoo.com
The Journal of Dermatology
|November 1, 2006
Summary
Eosinophilic cellulitis, also known as Wells' syndrome, is a rare skin condition. This report details a case with unusual annular lesions successfully treated with low-dose cyclosporine A.
Area of Science:
- Dermatology
- Pathology
Background:
- Eosinophilic cellulitis (Wells' syndrome) is a rare inflammatory skin condition with unknown causes.
- It typically presents as itchy, red plaques resembling cellulitis, with characteristic dermal eosinophilic infiltration and
- flame figures
- histologically.
Observation:
- This case report describes a patient presenting with atypical annular and semicircular lesions of eosinophilic cellulitis.
- The patient exhibited a unique clinical manifestation not commonly associated with this condition.
Findings:
- The patient's annular and semicircular eosinophilic cellulitis responded successfully to treatment with low-dose cyclosporine A.
- This suggests cyclosporine A as a potential therapeutic option for refractory or atypical presentations.
Implications:
- This case expands the understanding of the clinical spectrum of eosinophilic cellulitis.
- It highlights the efficacy of low-dose cyclosporine A in managing unusual variants of Wells' syndrome, offering a new treatment avenue.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Equilibrium and Balance
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Viral Meningitis
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
The Vestibular System
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
Anatomy of the Ear
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
