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Updated: Jul 19, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Therapeutic temperature modulation in neurocritical care
1Neurological Institute, 710 West 168th Street, Box 29, New York, NY 10032, USA. nbadjatia@neuro.columbia.edu
Abstract:
The ability to effectively achieve and maintain long-term temperature control is an important goal that has been previously unachievable in the neurocritical care setting. Previous attempts have been limited by the inability to overcome physiologic defense mechanisms, short duration of action, or significant adverse effects. Recent advances in technology have made therapeutic temperature modulation feasible. In this review, current concepts of therapeutic temperature modulation are presented. New advances in technology may provide an important breakthrough in the ability to reduce fever-associated morbidity in neurocritically ill patients. What remains to be seen is whether the advantages of these technologies will outweigh the risks associated with therapeutic temperature modulation.
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Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's forehead...

