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Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

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Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
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[Thoracic aortic dissection revealed by systemic cholesterol embolism].

L Braem1, P Paule, P Héno

  • 1Service de cardiologie, HIA Laveran, boulevard Alphonse-Laveran, BP 50, 13998 Marseille-Armées, France. docteur.louis@wanadoo.fr

Annales De Cardiologie Et D'Angeiologie
|November 3, 2006
PubMed
Summary

Cholesterol embolism syndrome, often linked to arterial procedures, can unmask a previously unknown aortic dissection. This rare association highlights the importance of specific diagnostic imaging.

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Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Nephrology

Background:

  • Systemic cholesterol embolism is a rare but serious complication of atherosclerosis.
  • While arterial catheterization is a known cause, its association with aortic dissection is exceptionally rare.
  • Cholesterol embolism syndrome presents with diverse clinical manifestations.

Observation:

  • A 70-year-old male with cardiovascular risk factors presented with purpuric lesions and acute renal failure, indicative of cholesterol embolism syndrome.
  • The patient had a history of coronary angioplasty and was found to have a descending thoracic aortic dissection with complex atheroma via transoesophageal echocardiography.
  • Clinical progression included digital ischemia and worsening renal failure necessitating hemodialysis.

Findings:

  • Transoesophageal echocardiography is crucial for diagnosing aortic dissection, especially in patients without typical thoracic symptoms.
  • Cholesterol embolism syndrome can be an unusual presenting sign of underlying aortic dissection.
  • Rupture of the intimal flap of the aortic dissection was confirmed on follow-up imaging.

Implications:

  • This case underscores the need for thorough cardiovascular evaluation in patients diagnosed with cholesterol embolism syndrome.
  • Transoesophageal echocardiography serves as a valuable, non-invasive tool for detecting aortic pathology in this context.
  • Recognizing this rare association can lead to earlier diagnosis and management of potentially life-threatening aortic dissections.