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Updated: Jul 19, 2026

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Systemic diseases among patients with and without alveolar bone loss
Abdulla Al-Emadi1, Nabil Bissada, Constantin Farah
1Department of Periodontics, School of Dental Medicine, Case Western Reserve University, Cleveland, Ohio 44106-4905, USA.
Individuals with moderate to severe alveolar bone loss show a higher prevalence of systemic diseases, particularly hypertension and diabetes. This highlights a significant link between periodontal health and overall well-being.
Area of Science:
- Oral Health and Systemic Disease Linkages
- Periodontology and Public Health
Background:
- Growing evidence suggests a connection between periodontal health and general health.
- Alveolar bone loss is a key indicator of periodontal disease severity.
Purpose of the Study:
- To compare the prevalence of common systemic diseases in patients with and without alveolar bone loss.
- Investigate the association between periodontal status and systemic conditions like hypertension, diabetes, respiratory diseases, arthritis, and allergies.
Main Methods:
- A cohort of 420 adults (≥18 years) was analyzed.
- Data included self-reported systemic diseases, demographics, smoking status, and periodontal parameters (alveolar bone level, teeth present).
- Statistical analyses employed Chi-square, Student t test, and logistic regression.
Main Results:
- Moderate to severe alveolar bone loss was significantly associated with higher prevalence of hypertension, respiratory diseases, diabetes, and arthritis.
- Hypertension and diabetes remained significant even after adjusting for confounding factors.
- Subjects with moderate to severe alveolar bone loss were four times more likely to have three or more systemic conditions.
Conclusions:
- Moderate to severe alveolar bone loss is linked to an increased prevalence of systemic diseases.
- Hypertension and diabetes mellitus are notably more common in individuals with significant alveolar bone loss.
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