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Organ Sparing Surgery for Penile Cancer: A Systematic Review
Mohamed H Kamel1, Nabil Bissada1, Renee Warford1
1Department of Urology, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Department of Urology, Baylor School of Medicine and Michael E. Debakey VA Medical Center, Houston, Texas (NB).
The Journal of Urology
|March 14, 2017
Summary
Organ sparing surgery for penile cancer offers comparable cancer control to traditional amputation. This approach improves quality of life and functional outcomes for selected patients.
Area of Science:
- Urology
- Surgical Oncology
- Oncology
Background:
- Penile cancer, though rare, necessitates treatment with significant functional and psychological impact.
- Traditional treatments like total or subtotal penectomy result in devastating outcomes.
- Organ-sparing surgery presents an attractive alternative for penile cancer management.
Purpose of the Study:
- To review organ-sparing surgical techniques for penile cancer.
- To evaluate the applicability and objective outcomes of these procedures.
- To provide guidance for urologists on penile cancer organ-sparing surgery.
Main Methods:
- A comprehensive literature search was performed using PubMed.
- Keywords included 'organ sparing/conserving,' 'penile cancer,' and various surgical techniques and outcomes.
- Focus on techniques ensuring complete tumor excision with negative margins.
Main Results:
- Organ-sparing surgery requires complete tumor excision with negative margins for efficacy.
- While local recurrence risk may be higher than amputation, overall survival remains unaffected.
- Cancer-specific survival is equivalent to established techniques with improved quality of life.
Conclusions:
- Organ-sparing surgery in selected penile cancer patients yields oncologic outcomes comparable to amputation.
- Patients retain the ability to urinate standing and a significant number can engage in intercourse.
- This approach offers improved quality of life and reduced morbidity.
