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Updated: Jul 19, 2026
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Metastases from a rectal adenocarcinoma to the prepuce]
Objective:
We report one case of metastatic dissemination of a rectal adenocarcinoma to the prepuce.
Methods:
61-year-old patient with the diagnosis of rectal adenocarcinoma treated 18 months before by surgery and chemotherapy. He presents with a painful enlargement of the penis associated with outgrowing erythematous lesions in the skin of the prepuce that bled on touch and did not allow the vision of the meatus and the glans penis. Physical examination showed the presence of hypogostric, penile and scrotal lymphedema. Circumcision was performed.
Results:
The pathologic study reported a moderately differentiated intestinal type adenocarcinoma with high mitotic index infiltrating the squamous cell flat epithelium of the prepuce.
Conclusions:
Although extremely rare, tumor implants in the prepuce secondary to extra urologic tumors are exceptional. Surgical excision confirms the origin and may avoid bleeding and discomfort, and also may help with catheterization, which is many times necessary in the final stages.
