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Published on: April 21, 2019
Comparison of two specific allergen screening tests in different patient groups
Yi-Hsun Liu1, Hsin-Hsu Chou, Ren-Long Jan
1Department of Pediatrics, National Cheng-Kung University Medical College, Tainan, Taiwan.
Acta Paediatrica Taiwanica = Taiwan Er Ke Yi Xue Hui Za Zhi
|November 3, 2006
Summary
UniCAP screening tests (Phadiatop and Fx5) and MAST showed differences in detecting allergies. UniCAP tests may be more effective for specific patient groups, particularly younger individuals and those with high IgE levels.
Area of Science:
- Allergy diagnostics
- Immunology
- Clinical chemistry
Background:
- Specific allergen tests like UniCAP and MAST are widely used.
- Phadiatop and Fx5 are UniCAP multi-allergen screening tests for inhalant and food allergens, respectively.
Purpose of the Study:
- To compare Phadiatop-Fx5 and MAST as screening allergen tests.
- To determine optimal screening tests for different allergic patient groups.
Main Methods:
- Serum samples from 224 allergic patients were tested using Phadiatop, Fx5, and MAST.
- Results were analyzed in subgroups based on age, serum IgE levels, and clinical departments.
Main Results:
- Inhalant allergen screening: Phadiatop positive in 69.2%, MAST in 61.1%.
- Food allergen screening: Fx5 positive in 25.4%, MAST in 14.3%.
- Disagreement between tests was higher for food allergens, especially in younger patients and those with IgE > 500 IU/ml.
Conclusions:
- UniCAP allergen screening tests demonstrate differences compared to MAST.
- UniCAP tests may offer greater effectiveness as screening tools for specific patient demographics.
