Related Experiment Video
Updated: Jul 19, 2026
06:46
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Diabetes mellitus screening in pediatric primary care
Shikha G Anand1, Supriya D Mehta, William G Adams
1Division of General Pediatrics, Boston University School of Medicine, Boston, Massachusetts, USA. shikha.anand@bmc.org
Pediatrics
|November 3, 2006
Summary
Pediatric diabetes screening is inconsistent with guidelines, missing opportunities to identify abnormal glucose metabolism in overweight youth. Improving adherence to screening recommendations is crucial for early detection and intervention in adolescents.
Area of Science:
- Pediatric Endocrinology
- Public Health
- Clinical Medicine
Background:
- Type 2 diabetes mellitus (T2DM) is increasingly diagnosed in children and adolescents.
- Overweight and obesity are significant risk factors for T2DM in pediatric populations.
- Current guidelines recommend T2DM screening for at-risk youth.
Purpose of the Study:
- To assess diabetes screening rates and identify screening abnormalities in overweight versus non-overweight adolescents.
- To evaluate adherence to American Diabetes Association (ADA) screening criteria in an urban primary care setting.
Main Methods:
- Retrospective chart review of 7710 patients aged 10-19 years in an urban primary care clinic.
- Data extracted from electronic health records between 2002 and 2004, including BMI, family history, and race.
- Analysis of screening rates based on ADA criteria and patient demographics.
Main Results:
- 42% of patients were overweight or at risk for overweight; 8.7% met ADA screening criteria.
- Screening rates were higher for those meeting ADA criteria (45.4%) but overall, less than half of eligible adolescents were screened.
- Abnormal glucose metabolism was detected in 9.2% of screened patients.
Conclusions:
- Pediatric diabetes screening is not consistently applied according to ADA guidelines.
- Systematic screening, potentially through point-of-care reminders, could improve detection of abnormal glucose metabolism in adolescents.
- Adherence to screening recommendations is vital for identifying at-risk youth and managing pediatric diabetes.
Related Concept Videos
01:25Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
01:15Diabetes: Symptoms, Diagnosis, and Complications
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
01:22Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
01:30Preventive Healthcare Services
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
01:22Diabetes Mellitus: Overview and Type I Subtype
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
01:29Hyperglycemia
Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose levels exceed 180 mg/dL two...