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Published on: July 20, 2022
Prevention of infectious complications in peritoneal dialysis: best demonstrated practices
F H Bender1, J Bernardini, B Piraino
1Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. benderf@dom.pitt.edu
Insights
Peritoneal dialysis (PD) infections like peritonitis are serious but preventable. Implementing strict protocols for catheter care, patient training, and infection monitoring can significantly reduce PD-related infection rates.
Area of Science:
- Nephrology
- Infectious Diseases
- Public Health
Background:
- Peritoneal dialysis (PD) related infections, particularly peritonitis, pose significant risks including hospitalization, catheter loss, and mortality.
- Infection rates vary considerably among PD patients and programs, indicating a need for targeted interventions.
Purpose of the Study:
- To highlight the importance of implementing comprehensive protocols to minimize PD-related infection risks.
- To emphasize the role of quality improvement initiatives and root cause analysis in managing PD infections.
Main Methods:
- Review of existing literature on PD infection prevention strategies.
- Discussion of protocols including catheter care, Staphylococcus aureus prophylaxis, patient training, and infection monitoring.
- Emphasis on continuous quality improvement and root cause analysis of infection episodes.
Main Results:
- Effective infection control in PD programs is achievable through meticulous attention to infection causes and risk reduction protocols.
- Key strategies include proper catheter placement, exit-site care with Staphylococcus aureus prophylaxis, thorough patient training, and prompt treatment of contamination.
- Quality improvement programs with continuous infection monitoring are crucial for reducing PD-related infections.
Conclusions:
- Peritonitis and exit-site infections in PD patients can be minimized with rigorous adherence to established protocols and continuous quality improvement.
- Further research is warranted to explore novel approaches for decreasing infection risk in PD patients.
- Systematic review of infection episodes to identify root causes is essential for effective PD program management.
Abstract:
Peritoneal dialysis (PD) related infections continue to be a serious complication for PD patients. Peritonitis can be associated with pain, hospitalization and catheter loss as well as a risk of death. Peritonitis risk is not evenly spread across the PD population or programs. Very low rates of peritonitis in a program are possible if close attention is paid to the causes of peritonitis and protocols implemented to reduce the risk of infection. Protocols to decrease infection risk in PD patients include proper catheter placement, exit-site care that includes Staphylococcus aureus prophylaxis, careful training of patients with periodic retraining, treatment of contamination, and prevention of procedure-related and fungal peritonitis. Extensive data have been published on the use of antibiotic prophylaxis to prevent exit site infections. There are fewer data on training methods of patients to prevent infection risk. Quality improvement programs with continuous monitoring of infections, both of the catheter exit site and peritonitis, are important to decrease the PD related infections in PD programs. Continuous review of every episode of infection to determine the root cause of the event should be routine in PD programs. Further research is needed examining approaches to decrease infection risk.
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