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Updated: Jul 19, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Repeat transseptal catheterization after ablation for atrial fibrillation
Gregory M Marcus1, Xiushui Ren, Zian H Tseng
1Division of Cardiology, Electrophysiology Section, University of California, San Francisco, California 94143-1354, USA. marcusg@medicine.ucsf.edu
Repeat transseptal catheterization after atrial fibrillation (AF) ablation is more difficult and less successful than the initial procedure. Complication rates may also increase, posing challenges for patients needing subsequent left atrial interventions.
Area of Science:
- Cardiology
- Electrophysiology
- Interventional Cardiology
Background:
- Many patients require repeat left atrial procedures after atrial fibrillation (AF) ablation.
- These procedures are often for left atrial flutter or recurrent AF.
- Success and complication rates of repeat transseptal catheterization are not well-established.
Purpose of the Study:
- To assess the difficulty and success rates of repeat transseptal catheterization following AF ablation.
- To identify potential complications associated with repeat procedures.
Main Methods:
- Consecutive patients undergoing repeat left atrial procedures after AF ablation were enrolled over one year.
- Data on difficulties, success rates, and complications of first and second transseptal catheterizations were recorded.
- Sixteen patients underwent repeat transseptal catheterization.
Main Results:
- Repeat transseptal catheterization was more difficult in 5 of 12 patients compared to their first procedure.
- Transseptal puncture was unsuccessful in 2 patients due to increased interatrial septal thickness.
- One repeat attempt was aborted due to posterior right atrial puncture and distorted anatomy.
Conclusions:
- Repeat transseptal catheterization after AF ablation is more challenging than the initial procedure.
- Success rates are lower, and complication risks may be higher in repeat procedures.
- This highlights potential difficulties in managing patients requiring subsequent left atrial interventions.
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