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Updated: Jul 19, 2026
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
Published on: January 3, 2011
[Clinical analysis of measuring corneal thickness with non-contact method]
Jia-qi Zhou1, Ren-yuan Chu, Xing-tao Zhou
1Department of Ophthalmology, the Eye Ear Nose and Throat Hospital of Fudan University, Shanghai 200031, China.
Objective:
To compare accuracy of the Pentacam with A-ultrasonoscope in the measurement of central corneal thickness.
Methods:
According to the degree of myopia, 107 myopic patients (211 eyes) were divided into four groups. The central corneal thickness was measured with the Pentacam system and A-ultrasonoscope. The results were compared statistically and the differences between these two methods were analyzed.
Results:
Mean values of central corneal thickness measured by the Pentacam system and A-ultrasonoscope was (535.58 +/- 36.34) microm and (536.73 +/- 37.18) microm, respectively. There was no difference in the results obtained by these two methods in each myopia group (P > 0.05). The 95% limits of agreement were (-1.88, -0.42).
Conclusions:
The data shows that the results obtained by Pentacam system do not have significant difference as compared with that from the A-ultrasonoscope. The Pentacam system can provide precise results and has the advantage of simplicity and non-contact. Therefore, it would be a promising instrument for the evaluation of central corneal thickness before the cornea refractive surgery.
