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InSatDb: a microsatellite database of fully sequenced insect genomes
Sunil Archak1, Eshwar Meduri, P Sravana Kumar
1Laboratory of Molecular Genetics, Centre for DNA Fingerprinting and Diagnostics, ECIL Road, Nacharam, Hyderabad 500 076, India.
Nucleic Acids Research
|November 4, 2006
Summary
InSatDb offers a searchable database of microsatellite information for five insect genomes. This tool aids in understanding microsatellite variations and facilitates comparative genomic analysis across species.
Area of Science:
- Genomics
- Bioinformatics
- Molecular Biology
Background:
- Microsatellites are repetitive DNA sequences crucial for genetic variation.
- Comprehensive databases are needed for studying microsatellites in diverse insect genomes.
Purpose of the Study:
- To develop an interactive interface, InSatDb, for querying insect microsatellite data.
- To provide detailed annotations and facilitate comparative genomic analysis.
Main Methods:
- Curated data from five fully sequenced insect genomes (fruit-fly, honeybee, malarial mosquito, red-flour beetle, silkworm).
- Development of an interactive web-based platform for data retrieval and analysis.
Main Results:
- InSatDb provides microsatellite data including size, genomic location, nature, and sequence composition.
- Users can access information on microsatellite clusters and conserved flanking sequences (paralogs).
Conclusions:
- InSatDb serves as a valuable resource for insect microsatellite research.
- The platform supports comparative genomic studies and detailed analysis of microsatellite characteristics.
