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Updated: Jul 19, 2026

Generation and Assembly of Virus-Specific Nucleocapsids of the Respiratory Syncytial Virus
Published on: July 27, 2021
Sulfonatocalixarenes: molecular capsule and 'Russian doll' arrays to structures mimicking viral geometry
Scott J Dalgarno1, Jerry L Atwood, Colin L Raston
1Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA. dalgarnos@missouri.edu
Abstract:
p-Sulfonatocalix[4,5,6,8]arenes are versatile building blocks, able to assemble into 'molecular capsule' arrays based on two calixarenes, as well as a variety of other structural motifs, with the extended structures dominated by the formation of bilayers. For p-sulfonatocalix[4]arene, assembly into nanometre scale spheroids (of either icosahedral or cuboctahedral geometries) as well as nanotubules (all of which take on structural features akin to those of viruses) is possible, depending on the guest molecules and lanthanides present in solution.
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