Multi-modal detection methods based on vortex fluid device mediated red-emitting carbon dots for sensitive vitamin B6
Yanan Yan1, Hongping Zhang2, Youhong Tang3
1Institute of Environmental Science and College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, Shanxi, China.
Food Chemistry
|April 10, 2026
Summary
This study introduces a portable, multi-modal sensor for Vitamin B6 (VB6) detection, overcoming limitations of traditional methods. The novel sensor offers accurate quantification in food analysis with high sensitivity and reliability.
Area of Science:
- Analytical Chemistry
- Materials Science
- Biochemistry
Background:
- Conventional Vitamin B6 (VB6) quantification methods suffer from poor anti-interference and unreliable results.
- Short-wavelength detection techniques limit accuracy in complex food matrices.
Purpose of the Study:
- To develop a portable, long-wavelength, multi-modal sensing platform for accurate VB6 detection.
- To address the limitations of existing methods in food analysis.
Main Methods:
- Synthesis of red-emitting carbon dots (R-CDs) using a vortex fluidic device-assisted solvothermal strategy.
- Development of a multi-modal sensing platform integrating fluorescence, UV absorption, and smartphone-based visual detection.
- Utilizing the fluorescence quenching and spectral shifts of R-CDs upon binding with VB6.
Main Results:
- R-CDs exhibited uniform size, red emission (616 nm), and high quantum yield (71.5%).
- The sensing platform achieved a low limit of detection of 0.87 μg/mL for VB6.
- High recovery rates (100.09-102.86%) were observed in real food samples, demonstrating practical applicability.
Conclusions:
- The developed multi-modal sensing strategy provides a versatile and accurate method for VB6 detection in complex matrices.
- This work advances the application of carbon dot-based sensors for high-accuracy analyte quantification.
- The cross-validation approach enhances the reliability of the sensing platform.
