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Updated: Jul 19, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Multiple myeloma involving the thyroid cartilage.
Taketoshi Shimada1, Masahiro Matsui, Kaichiro Ikebuchi
1Department of Otolaryngology, Head and Neck Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-0841, Japan. tshimada@koto.kpu-m.ac.jp
This study details a rare case of multiple myeloma affecting the thyroid cartilage in a 72-year-old male. The patient successfully responded to irradiation without adjuvant therapy, showing no disease progression over three years.
Area of Science:
- Oncology
- Hematology
- Laryngology
Background:
- Plasma cell neoplasms, including multiple myeloma, present a spectrum of disease.
- Extramedullary plasmacytoma in the larynx is uncommon, particularly involving the thyroid cartilage.
Observation:
- A 72-year-old male presented with a pathological cervical vertebrae fracture.
- CT revealed low-density lesions within the thyroid cartilage, with intact laryngeal mucosa.
- Tumors in the thyroid cartilage and vertebrae showed plasmacytoma, leading to a multiple myeloma diagnosis.
Findings:
- The patient received irradiation for laryngeal and cervical vertebrae lesions.
- No aggressive changes or new lesions were observed during a 3-year follow-up.
- The treatment was effective without the need for adjuvant therapy.
Implications:
- This case highlights the possibility of thyroid cartilage involvement in multiple myeloma.
- It underscores the effectiveness of localized irradiation for rare plasmacytoma presentations.
- Further research may elucidate optimal management strategies for laryngeal plasma cell neoplasms.
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