Related Experiment Video
Updated: Jul 19, 2026

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
Published on: May 27, 2022
Hormonal abnormalities in azoospermic men in Kano, Northern Nigeria
M A Emokpae1, P O Uadia, A Z Mohammed
1Department of Chemical Pathology, Aminu Kano Teaching Hospital, Kano, Nigeria. biodunemokpae@yahoo.com
Background & Objectives:
We undertook this study to observe the pattern of hormonal abnormalities and testicular pathology in azoospermic male Africans in Kano, Northern Nigeria.
Methods:
Eighty consecutive azoospermic infertile males attending fertility clinic in Aminu Kano Teaching Hospital, Kano, were selected for the study. Their semen were analyzed three times at eight weeks interval, after which serum follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone and prolactin were assayed in serum samples, and histological examination of testicular biopsies done.
Results:
Of the 80 subjects studied, 32 (40%) had abnormal hormonal levels, 48 (60%) had normal hormonal values and 36 (45%) had testicular pathology.
Interpretation & Conclusion:
Endocrinopathies are common in azoospermia. Their contribution to male factor infertility cannot be overemphasized. The main reason for the endocrinopathies is not known but environmental factors, endocrine disruptors and genetic polymorphism have been suggested to be contributory.
Related Concept Videos
Infertility in Males
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Spermatogenesis
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of endometrial...
Menopause
Oogenesis