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Related Experiment Videos

dbRES: a web-oriented database for annotated RNA editing sites.

Tao He1, Pufeng Du, Yanda Li

  • 1Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China.

Nucleic Acids Research
|November 8, 2006
PubMed
Summary
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A new public database, dbRES, consolidates experimentally verified RNA editing sites. This resource aids researchers in studying RNA editing and developing predictive computational algorithms.

Area of Science:

  • Bioinformatics
  • Molecular Biology
  • Genomics

Background:

  • Experimental data on RNA editing sites is abundant but fragmented across various sources and formats.
  • A centralized, high-quality resource is crucial for systematic RNA editing research and computational algorithm development.

Purpose of the Study:

  • To establish dbRES, a public database for experimentally validated RNA editing sites.
  • To provide a user-friendly platform for accessing and analyzing RNA editing data.

Main Methods:

  • Manual curation of RNA editing sites from scientific literature and GenBank annotations.
  • Development of a public database (dbRES) with a web interface for data retrieval and visualization.

Main Results:

Related Experiment Videos

  • dbRES version 1.1 contains 5,437 RNA editing sites from 251 transcripts across 96 organisms.
  • The database includes comprehensive annotations such as transcript sequences, editing types, locations, and organismal information.

    • Conclusions:

    • dbRES offers a valuable, standardized resource for the scientific community studying RNA editing.
    • The database facilitates research in RNA editing mechanisms and the development of predictive tools.