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[Genital herpes].

C J Adam1, M Staehler, W Khoder

  • 1Urologische Klinik und Poliklinik, Klinikum der Ludwig-Maximilians-Universität, Marchioninistrasse 15, 81377 München, Deutschland. christoph.adam@med.uni-muenchen.de

Der Urologe. Ausg. A
|November 8, 2006
PubMed
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Genital herpes simplex virus (HSV) infection is a lifelong, recurring STI. Transmission occurs via skin contact, often during asymptomatic shedding, with diagnosis via clinical, microbiologic, and serologic methods.

Area of Science:

  • Virology
  • Epidemiology
  • Immunology

Context:

  • Genital herpes simplex virus (HSV-1 and HSV-2) is a significant global sexually transmitted disease (STD).
  • Transmission occurs through direct skin contact, frequently during periods of asymptomatic viral shedding.
  • The virus establishes latency in the dorsal root ganglion, evading the host immune system.

Purpose:

  • To summarize the epidemiology, transmission, pathogenesis, diagnosis, and treatment of genital herpes simplex virus infections.
  • To highlight the increasing global health importance of HSV infections.

Summary:

  • Genital herpes is a lifelong, ulcerative, and recurrent STD caused by HSV-1 and HSV-2.
  • The primary risk factor is the number of lifetime sexual partners.

Related Experiment Videos

  • Diagnosis involves clinical evaluation, microbiological testing, and serological assays.
  • Virostatic agents are available for managing outbreaks and reducing transmission.

    • Impact:

    • Understanding HSV transmission and pathogenesis is crucial for public health interventions.
    • Effective diagnosis and management strategies can mitigate the impact of this widespread infection.
    • Continued research into HSV is vital for developing improved prevention and treatment options.