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Complementary DNA01:44

Complementary DNA

Overview
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
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The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

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Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
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Cell instructive polymers.

Takuya Matsumoto1, David J Mooney

  • 1Division of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA. tmatsu@deas.harvard.edu

Advances in Biochemical Engineering/Biotechnology
|November 9, 2006
PubMed
Summary
This summary is machine-generated.

Cell instructive polymers are advanced materials that actively guide tissue development by controlling cell behavior. Recent designs focus on precise spatial and temporal delivery of cues to regulate tissue structure and function.

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Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Polymer Chemistry

Background:

  • Polymeric materials in tissue engineering have evolved from simple cell delivery vehicles.
  • Current applications involve active regulation of tissue structure and function.

Purpose of the Study:

  • To outline recent trends in the design of cell instructive polymers.
  • To highlight how these materials control cell function and tissue formation.

Main Methods:

  • Spatial and temporal regulation of cues (e.g., adhesion ligands, growth factors).
  • Design of polymeric materials to interact with and instruct cells.

Main Results:

  • Polymeric materials can actively direct tissue development.
  • Cell instructive polymers offer precise control over cellular responses.

Conclusions:

  • Cell instructive polymers represent a significant advancement in tissue engineering.
  • Future designs will likely focus on sophisticated control over cellular microenvironments.