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Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Updated: Jul 19, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Childhood asthma: breakthroughs and challenges.

Henry Milgrom¹

¹University of Colorado Health Sciences Center, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA. milgromh@njc.org

Advances in Pediatrics

|November 9, 2006

Summary

Controlling asthma requires a multi-faceted approach, including environmental, genetic, and mechanistic strategies. Improving asthma prevention and management through research and clinical practice is crucial for reducing disparities.

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Last Updated: Jul 19, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Area of Science:

Allergy and immunology
Public health
Genetics

Background:

Asthma and allergic disorders pose significant public health challenges.
Current understanding suggests potential interventions targeting environmental, dietary, infectious, and genetic factors.
Existing disparities in asthma prevalence and severity necessitate improved prevention and management strategies.

Purpose of the Study:

To outline a comprehensive strategy for the control and elimination of asthma and allergic disorders.
To explore diverse approaches including primary, secondary, and tertiary prevention.
To bridge the gap between basic research and clinical practice for effective asthma management.

Main Methods:

Review of current and potential future strategies for asthma control.
Analysis of disease prevention stages: primary, secondary, and tertiary.
Emphasis on the need for reliable diagnostic criteria and longitudinal studies.
Discussion on physician adoption of controller therapies and patient identification.

Main Results:

Multiple avenues for asthma control exist, including environmental manipulation, genetic profiling, and mechanistic interventions.
Understanding causative factors at each prevention level is key to translating knowledge into practice.
Closing the gap between research and healthcare delivery is essential.

Conclusions:

A combination of approaches, from environmental modifications to genotype-specific treatments, is needed to control asthma.
Effective asthma management requires improved diagnostics, physician buy-in for controller therapies, and enhanced patient adherence.
Translating scientific knowledge into clinical practice and public health policy is paramount for reducing asthma disparities.