Expression of the mRNA for the ligand of c-kit in mouse Sertoli cells
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P Rossi1, C Albanesi, P Grimaldi
1Department of Public Health and Cell Biology, II University of Rome Tor Vergata, Italy.
Biochemical and Biophysical Research Communications
|April 30, 1991
Abstract:
The expression of the mRNA for SLF (the c-kit ligand), a product of the "steel" locus, has been investigated in postnatal mouse testis and homogeneous populations of testicular cells. The message was found expressed in postnatal mouse testis but not in germ cells. Studies on primary mouse Sertoli cell cultures from 18 day old mice show that Sertoli cells are the site of SLF mRNA expression in the seminiferous tubules. Treatment of Sertoli cell cultures with cAMP analogs led to a significant increase in the SLF mRNA levels.