Related Experiment Video
Updated: Jul 19, 2026

09:37
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
Xanthusbase: adapting wikipedia principles to a model organism database
Bradley I Arshinoff1, Garret Suen, Eric M Just
1Department of Biology, Syracuse University, Syracuse, NY 13244, USA.
Nucleic Acids Research
|November 9, 2006
Summary
xanthusBase is a new model organism database for Myxococcus xanthus, a bacterium studied for prokaryotic multicellularity and biofilms. It uses open-source software and a Wikipedia-style model for easy navigation and community genome annotation.
Area of Science:
- Microbiology
- Bioinformatics
- Genomics
Background:
- Myxococcus xanthus is a key model organism for studying prokaryotic multicellularity.
- Understanding multicellularity is crucial for research on biofilms in basic and applied microbiology.
- Existing model organism databases (MODs) can be enhanced for specific organisms.
Purpose of the Study:
- To introduce xanthusBase, the official model organism database for Myxococcus xanthus.
- To create a user-friendly and highly navigable resource for M. xanthus research.
- To leverage community contributions for genome annotation.
Main Methods:
- Development of xanthusBase utilizing open-source software.
- Integration of established platforms like Generic Model Organism Database (GMOD) and MediaWiki.
- Implementation of a Wikipedia-style, interactive curation model.
Main Results:
- xanthusBase provides a dedicated, official database for Myxococcus xanthus.
- The database is designed for high utility and ease of navigation.
- A community-driven annotation model is established, enabling researcher contributions.
Conclusions:
- xanthusBase enhances the study of Myxococcus xanthus and prokaryotic multicellularity.
- The database facilitates collaborative genome annotation through its interactive design.
- This resource supports ongoing research in microbiology and biofilm formation.
Related Concept Videos
Gene Families
Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Synthetic Biology
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
Genetic Screens
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

