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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

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Related Experiment Video

Updated: Jul 19, 2026

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

Management of intestinal failure.

K Soondrum1, R Hinds

  • 1Department of Child Health, King's College Hospital, London, United Kingdom.

Indian Journal of Pediatrics
|November 9, 2006
PubMed
Summary

Intestinal failure (IF) management focuses on achieving enteral autonomy to wean patients from costly parenteral nutrition (PN). Early enteral feeding and potential therapies aid intestinal adaptation, improving outcomes for short bowel syndrome (SBS).

Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Nutritional Support

Background:

  • Intestinal failure (IF) results from loss of functional small bowel, often leading to short bowel syndrome (SBS).
  • Parenteral nutrition (PN) is the primary treatment for IF but carries risks like liver disease (PNALD) and sepsis.
  • Achieving enteral autonomy is crucial to discontinue PN and mitigate its complications.

Purpose of the Study:

  • To review current strategies for managing intestinal failure and promoting intestinal adaptation.
  • To discuss the role of enteral nutrition, pharmacological agents, and surgical interventions in achieving enteral autonomy.
  • To highlight the need for more pediatric data on therapies aimed at enhancing intestinal adaptation.

Main Methods:

  • Review of literature on intestinal failure, short bowel syndrome, and intestinal adaptation.

More Related Videos

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

Related Experiment Videos

Last Updated: Jul 19, 2026

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

  • Discussion of management strategies including parenteral nutrition, enteral feeding, and pharmacological adjuncts.
  • Exploration of surgical options such as bowel lengthening and transplantation.

    • Main Results:

    • Enteral feeds are a key stimulant for intestinal adaptation, increasing absorptive capacity.
    • Pharmacological agents like glutamine, growth hormone, and GLP-2 may aid adaptation, but pediatric data is limited.
    • Surgical interventions and, in severe cases, small bowel transplantation are options when other methods fail.

    Conclusions:

    • Early initiation of enteral feeds is vital for promoting intestinal adaptation and achieving independence from PN.
    • Further research is needed, particularly in pediatrics, to optimize the use of adjunct therapies for IF.
    • Small bowel transplantation remains a critical option for IF patients with irreversible complications or PN intolerance.