Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A flexible transcutaneous oxygen sensor using polymer membranes.

Hiroyuki Kudo1, Shigehito Iguchi, Takua Yamada

  • 1Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.

Biomedical Microdevices
|November 9, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Headset-Type Biofluorometric Gas Sensor with CMOS for Transcutaneous Ethanol from the Ear Canal.

Sensors (Basel, Switzerland)·2026
Same author

Highly Sensitive Fluorometric Acetone Biosensor Using Hemi-Ellipsoidal Mirror Optics for Efficient Light Collection.

ACS sensors·2026
Same author

High-sensitivity isopropanol Biomeasurement using enzyme cycling reactions.

Talanta·2025
Same author

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Real-Time Continuous Tongue Pressure Measurement With Mouthguard-Type Pressure-Sensing Device.

Orthodontics & craniofacial research·2025
Same author

Compressed sensing-based image reconstruction for discrete tomography with sparse view and limited angle geometries.

PloS one·2025
Same journal

A pump-free gravity-driven microfluidic chip for rapid RPA-LFS-based detection of Magnaporthe oryzae AvrPi9 gene.

Biomedical microdevices·2026
Same journal

Mechanotherapeutic biomaterials: Overcoming physical barriers to enhance intratumoral drug delivery in solid tumours.

Biomedical microdevices·2026
Same journal

Reversibly-sealable microfluidic platform for multi-molecule gradient delivery to large adherent cell cultures.

Biomedical microdevices·2026
Same journal

3D printed chip as platform to vascularize hiPSCs-derived kidney organoids.

Biomedical microdevices·2026
Same journal

Ingestible smart capsules: from engineering innovation to GI drug delivery.

Biomedical microdevices·2026
Same journal

An inexpensive, portable, refrigeration-free, ready-to-use microfluidic device for real-time multiplexed molecular detection of HIV, HBV, and HCV.

Biomedical microdevices·2026
See all related articles

A flexible, wearable oxygen sensor was developed for monitoring blood oxygen levels non-invasively. This innovative device successfully tracked transcutaneous oxygen in human subjects, demonstrating its practical application in healthcare.

Area of Science:

  • Biomedical Engineering
  • Sensor Technology
  • Materials Science

Background:

  • Transcutaneous blood gas monitoring is crucial for patient care.
  • Existing methods can be invasive or lack flexibility.
  • Development of wearable sensors offers a promising alternative.

Purpose of the Study:

  • To fabricate and evaluate a wearable, flexible oxygen sensor for transcutaneous blood gas monitoring.
  • To assess the sensor's performance in electrochemical measurements and physiological applications.

Main Methods:

  • Fabrication of a laminar film-like sensor using a KCl electrolyte, non-permeable sheet, and gas-permeable membrane.
  • Integration of Pt- and Ag/AgCl-electrodes via microfabrication.
  • Electrochemical measurements and transcutaneous oxygen monitoring on human subjects.

Related Experiment Videos

Main Results:

  • The sensor demonstrated a wide calibration range (0.0–7.0 mg/l dissolved oxygen) with high linearity (R²=0.998).
  • Achieved a rapid response time of 53.4 seconds to reach 90% steady-state current.
  • Successfully monitored transcutaneous oxygen variations in human subjects inhaling different oxygen concentrations without adverse skin reactions.

Conclusions:

  • The developed wearable oxygen sensor is effective for transcutaneous blood gas monitoring.
  • The sensor exhibits excellent performance comparable to commercial electrodes.
  • This technology offers a comfortable and reliable non-invasive method for oxygen level assessment.