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Published on: May 16, 2025
Pain in children with rheumatic diseases
1Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, 30 Prospect Ave., Hackensack, NJ 07601, USA. ykimura@humed.com
Insights
Pain management in pediatric rheumatic diseases is complex, as pain impacts children's daily lives despite treatment advances. A multifactorial approach beyond disease treatment is crucial for effective pain relief.
Area of Science:
- Pediatric Rheumatology
- Pain Management
- Child Health
Background:
- Pain is a prevalent issue in children with rheumatic diseases, significantly affecting their daily functioning and quality of life.
- Current arthritis treatments do not fully resolve pain, and a standardized pain management protocol is lacking.
- The origins of pain in these children are diverse, indicating that solely treating the underlying rheumatic disease may be insufficient.
Purpose of the Study:
- To review current pain management strategies for children with rheumatic diseases.
- To highlight the multifactorial nature of pain in this population.
- To provide guidance on appropriate and inappropriate treatment modalities.
Main Methods:
- Literature review of existing pain management practices in pediatric rheumatic diseases.
- Analysis of current pharmacologic and non-pharmacologic treatment options.
- Discussion of the role of disease-specific treatments versus general pain relief.
Main Results:
- Standard treatments include acetaminophen, nonsteroidal anti-inflammatory drugs, methotrexate, and etanercept.
- Non-pharmacologic interventions like exercise and cognitive-behavioral therapy are important considerations.
- Opioids may be necessary for refractory pain, while systemic corticosteroids should be avoided for pain management in arthritis.
Conclusions:
- Effective pain management in pediatric rheumatic diseases requires a comprehensive, multifactorial approach.
- Treatment should integrate disease-modifying drugs with targeted pain relief strategies.
- Careful consideration of treatment options, avoiding systemic corticosteroids, is essential for optimizing outcomes.
Abstract:
Pain is common in rheumatic diseases in children. Despite recent advances in arthritis treatment, pain continues to be a problem impacting daily functioning and quality of life, and no standard of care for pain management exists. The pathogenesis of pain in children with rheumatic diseases is multifactorial, and treatment of the disease alone may not be enough. Current pain treatment often includes acetaminophen, nonsteroidal anti-inflammatory drugs, and medications that treat arthritis such as methotrexate and etanercept. Nonpharmacologic interventions, such as exercise and cognitive-behavioral therapy as well as the use of analgesics such as opioids in patients whose pain is refractory to standard therapies, should also be considered. The use of systemic corticosteroids to treat pain in children with arthritis should be avoided. Idiopathic pain may coexist in children with rheumatic disease, but treatment of idiopathic pain is different than that of pain due to inflammatory disorders.
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