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Direct interaction between ER membrane-bound PTP1B and its plasma membrane-anchored targets

Ines Anderie1, Irene Schulz, Andreas Schmid

  • 1Department of Physiology, University of the Saarland, D-66421, Homburg/Saar, Germany.

Cellular Signalling
|November 10, 2006
PubMed
Summary

Protein tyrosine phosphatase PTP1B interacts with plasma membrane proteins while anchored to the ER. This occurs at membrane junctions, enabling cellular signaling communication between the ER and plasma membrane.

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