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The PROTICdb database for 2-DE proteomics.

Olivier Langella1, Michel Zivy, Johann Joets

  • 1UMR de Génétique Végétale, La Ferme du Moulon, Gif-sur-Yvette, France.

Methods in Molecular Biology (Clifton, N.J.)
|November 10, 2006
PubMed
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PROTICdb is a new database for plant proteome data analysis. It aids in storing, tracking, and interpreting proteomic experiment results, supporting detailed biological insights.

Area of Science:

  • Proteomics
  • Bioinformatics
  • Plant Science

Background:

  • Plant proteome research generates vast datasets.
  • Analyzing proteomic data requires specialized tools for storage and interpretation.
  • Existing databases may lack comprehensive features for plant-specific proteomic workflows.

Purpose of the Study:

  • To develop PROTICdb, a web-based database for plant proteome data.
  • To facilitate storage, tracking, and querying of proteomic experimental data.
  • To integrate diverse data sources for enhanced interpretation of plant proteomic results.

Main Methods:

  • Utilizes 2D polyacrylamide gel electrophoresis (2D PAGE) and mass spectrometry (MS) for data generation.
  • Supports data input via software outputs (e.g., PDQuest, Mascot) and web forms.

Related Experiment Videos

  • Features a GelBrowser for visualizing and querying 2D PAGE maps.

    • Main Results:

    • PROTICdb enables comprehensive management of plant proteomic data.
    • It allows for the integration of experimental data with external knowledge.
    • Quantitative data export facilitates statistical analysis with third-party software.

    Conclusions:

    • PROTICdb provides a valuable resource for plant proteomics research.
    • The database supports detailed analysis, including allelic variant and post-translational modification identification.
    • PROTICdb is freely available, promoting wider accessibility and collaboration in the field.