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Updated: Jul 18, 2026

Artificial Antigen Presenting Cell (aAPC) Mediated Activation and Expansion of Natural Killer T Cells
Published on: December 29, 2012
Primary adrenal natural killer/T-cell nasal type lymphoma: first case report in adults
Michael A Thompson1, Mouhammed A Habra, Mark J Routbort
1Division of Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA. micthompson@mdanderson.org
Abstract:
We report the first case of a primary adrenal natural killer (NK)/T-cell nasal type lymphoma in adults. The patient presented with an enlarging left adrenal mass and the initial concern was for adrenocortical carcinoma. Surgical resection revealed NK/T-cell lymphoma. Rapid recurrence in the contralateral adrenal gland was treated with a single cycle of chemotherapy before he died due to infectious complications and progressive disease. This case demonstrates the aggressive presentation of a novel subset of primary adrenal lymphoma that should be considered in the differential diagnosis of a rapidly enlarging adrenal mass.