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Updated: Jul 18, 2026

A Toxicological and Ecotoxicological Assay Based on Mussel (Mytilus galloprovincialis) Hemocytes Motility
Published on: December 13, 2024
[Study on the molluscicidal effect of META-Li against Oncomelania hupensis]
Dan Zhu1, Xiao-nong Zhou, Si-qing Zhang
1National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
Objective:
To evaluate the molluscicidal effect of the META-Li (40% META liquid formulation) against Oncomelania snails in laboratory and field.
Methods:
The experiment of META-Li against the snails by spraying, immersion and climbing-inhibition test was carried out in laboratory. Spray method was performed in the field to compare with the wettable powder of 50% niclosamide ethanolamine salt.
Results:
In laboratory, the LC50 of META-Li by spraying for 1, 2, 3 days was 0.78, 0.44 and 0.46 g/m2 respectively; by immersion method for 1, 2, 3 days, it was 44.4, 27.4 and 24.8 mg/L respectively. When sprayed with active ingredient 2 g/mW of META-Li in the field, the snail death rate was above 90% after 7 days, similar to that of niclosamide.
Conclusion:
META-Li shows high molluscicidal and climbing-inhibition effect on Oncomelania snails.

