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Related Experiment Video

Updated: Jul 18, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

WormBase: new content and better access.

Tamberlyn Bieri¹, Darin Blasiar, Philip Ozersky

¹Genome Sequencing Center, Washington University School of Medicine, St Louis, MO 63108, USA. tbieri@watson.wustl.edu

Nucleic Acids Research

|November 14, 2006

Summary

WormBase, a key resource for nematode research, has been updated with new genetic and genomic data for Caenorhabditis elegans and related species. Enhanced features improve data accessibility and searchability for the scientific community.

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Worm-align and Worm_CP, Two Open-Source Pipelines for Straightening and Quantification of Fluorescence Image Data Obtained from Caenorhabditis elegans

Worm-align and Worm_CP, Two Open-Source Pipelines for Straightening and Quantification of Fluorescence Image Data Obtained from Caenorhabditis elegans

Published on: May 28, 2020

Area of Science:

* Nematode genomics and bioinformatics
* Model organism databases
* Functional genomics and cell biology

Background:

* WormBase is a central repository for data on Caenorhabditis elegans and related nematodes.
* Continuous updates are essential for maintaining a comprehensive and current research resource.

Purpose of the Study:

* To report on the recent expansions and improvements to the WormBase database.
* To highlight new datasets and enhanced functionalities for researchers.

Main Methods:

* Integration of new classical genetics, cell biology, and functional genomics data for C. elegans.
* Development of a new genome browser for Caenorhabditis remanei.
* Deployment of upgraded hardware for improved database performance.

Main Results:

* Significant increase in content for phenotype descriptions and RNAi experiments.
* Addition of new datasets including C. remanei draft assembly and annotations, Vancouver Fosmid library, and TEC-RED 5' end sites.
* Improved access and search flexibility through multiple mirror sites and Google indexing.

Conclusions:

* WormBase continues to be a vital, evolving resource for nematode research.
* Recent updates enhance the breadth of data and user accessibility, supporting a wide range of biological investigations.